Figure 5.

y-PSNPs internalization and accumulation in Caco-2 cells throughout eight weeks of exposure to 0.26 μg/cm². Percentage of fluorescent Caco-2 cells (A), indicating y-PSNPs internalization, and relative fluorescence intensity of cells, compared to untreated cells (B), indicating y-PSNPs accumulation, at 24, 48, and 96 h and weekly are shown. Values are plotted as means for all three replicates and SEM of each treatment group. Statistical significance was determined by two-way ANOVA. ** p ≤ 0.01, *** p ≤ 0.001.