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. 2021 Sep 29;9(10):1356. doi: 10.3390/biomedicines9101356
AGE advanced glycation end-product
Akt protein kinase B
AMPK AMP-protein kinase
Ang angiotensin
BP blood pressure
CHD coronary heart disease
CVD cardiovascular disease
CVOT cardiovascular outcome trial
EC endothelial cell
ED endothelial dysfunction
EDHF endothelium-derived hyperpolarizing factor
eNOS endothelial nitric oxide synthase
FMD flow mediated dilation
HAECs human aortic endothelial cells
HbA1c glycosylated hemoglobin
HCAECs human coronary arterial ECs
HF heart failure
HFpEF HF with preserved ejection fraction
HFrEF HF with reduced ejection fraction
HG high glucose
HUVECs human umbilical vein endothelial cells
ICAM-1 intercellular adhesion molecule-1
IL-1β interleukin β
IL6 interleukin 6
I/R ischemia/reperfusion
JNK c-Jun N-terminal kinase
LV left ventricle
MCP-1 monocyte chemoattractant protein-1
MPs microparticles
NFkB nuclear factor kappa-light-chain-enhancer of activated B cells
NHE1 sodium-hydrogen exchanger 1
NO nitric oxide
NOX NADPH oxidase
PI3K phosphatidylinositol 3-kinase
PKC protein kinase C
PKG protein kinase G
PWV pulse wave velocity
RAGE receptor for AGE
ROS reactive oxygen species
RH-PAT reactive hyperemia peripheral arterial tonometry
SGLT2-I sodium-glucose cotransporter-2 inhibitor
STZ streptozotocin
T2DM type 2 diabetes mellitus
TNFα tumor necrosis factor α
VCAM-1 vascular cell adhesion molecule-1
ZDF rats Zucker diabetic fatty rats