Figure 6.

Effect of Ashwagandha extracts and purified withanolides on metal and heat-shock-induced protein aggregation. (A) Protein aggregation and deaggregation assay showing the GFP aggregation in sodium-(meta)arsenite-treated cells and deaggregation after incubation with Ashwagandha withanolides. (B) Luciferase activity in heat-shock was treated and recovered either in control or Ashwagandha-withanolides-supplemented medium. Quantitation of the results is shown below (mean ± SD, n = 3), * p < 0.05, ** p < 0.01, *** p < 0.001 (Student’s t-test).