Figure 5.

In renal tissues, effects of SAC on the protein expression induced by cisplatin, including (A) anti-oxidative enzymes (catalase, SOD1 and GPx3) and (B) HO-1 and Nrf2. The protein levels of anti-oxidative enzymes HO-1 and Nrf2 protein expression in renal homogenates were assessed by Western blot analysis after a cisplatin challenge. The analysis of protein bands was carried out by densitometric analysis. The values are reported as the mean ± SEM (n = 3). ^## p < 0.01 and ^### p < 0.001 compared with the control group; * p < 0.05, ** p < 0.01 and *** p < 0.001 compared with the cisplatin-only group.