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. 2021 Oct 15;10(10):1620. doi: 10.3390/antiox10101620

Table 1.

SAC changes the body weight and the kidney index in cisplatin-associated nephrotoxicity. The data are presented as the mean ± SEM (n = 6). ### p < 0.001 compared with the control group. ** p < 0.01 and *** p < 0.001 compared with the cisplatin-only group.

Groups Initial Body Weight (g) Final Body Weight (g) Kidney Index (mg/g)
Control 29.8 ± 0.53 31.87 ± 0.45 1.34 ± 0.02
Cisplatin (20 mg/kg) 29.93 ± 0.65 25.72 ± 0.98 ### 2.22 ± 0.08 ###
Cisplatin (20 mg/kg) + AMF (200 mg/kg) 30.03 ± 0.21 30.27 ± 0.21 *** 1.51 ± 0.02 ***
Cisplatin (20 mg/kg) + SAC (5 mg/kg) 29.85 ± 0.39 26.62 ± 0.52 2.07 ± 0.07 **
Cisplatin (20 mg/kg) + SAC (10 mg/kg) 30.1 ± 0.28 29.1 ± 0.53 *** 1.66 ± 0.04 ***
Cisplatin (20 mg/kg) + SAC (20 mg/kg) 30.0 ± 0.37 29.45 ± 0.17 *** 1.56 ± 0.02 ***