Figure 3.
BODY FUNCTION—mobility and forelimb grip strength. 1. General mobility. (A) Bizarre gait patterns; (B) incidence of freezing; the results are expressed as incidence (%). Statistics: Fisher’s exact test, Age effect is expressed as (A); Genotype effect is expressed as (G); Genotype and Age interaction effect is expressed as (GxA); * p < 0.05, ** p < 0.01 and *** p < 0.001. (C) Freezing—latency movement; 2. Forelimb grip strength—Hanger Test. (D) Muscular Strength—latency; (E) Muscular Strength—distance; (F) Muscular Endurance—latency; (G) Muscular Endurance—distance, the results are expressed as mean ± SEM. Statistics: one-way ANOVA, Age effect expressed as (A); Genotype effect expressed as (G); Genotype and Age interaction effect is expressed as (GxA). * p < 0.05, ** p < 0.01, and *** p < 0.001 followed by post hoc Bonferroni test, * p < 0.05, ** p < 0.01, and *** p < 0.001; differences between NTg vs. 3xTg-AD are expressed (g): # p < 0.05; differences between age in NTg group are expressed (a): &&& p < 0.001, and for 3xTg-AD group are expressed (a): $ p < 0.01.