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. 2021 Sep 22;9(10):1287. doi: 10.3390/biomedicines9101287

Table 2.

Comparison of the two decontamination techniques (by virus removal by ultrafiltration [28] or UVC inactivation) used in this study.

Advantages Ultrafiltration UVC Irradiation
Cheap Yes Yes
Rapid Yes Yes
Applicable for large volume Up to 70 mL/time Yes
Applicable in BSL3 Yes (only centrifuge required) Yes (although might be difficult to set and control radiation)
Complete and efficient active virus removal Yes Yes
Recovery Poor. Sample interacts with the filter causing sample loss Good. Disassembly of the dimeric/trimeric forms of IL-8, IL-10 and TNF-α
Cytokine profiling Yes Yes