Table 2.
Advantages | Ultrafiltration | UVC Irradiation |
---|---|---|
Cheap | Yes | Yes |
Rapid | Yes | Yes |
Applicable for large volume | Up to 70 mL/time | Yes |
Applicable in BSL3 | Yes (only centrifuge required) | Yes (although might be difficult to set and control radiation) |
Complete and efficient active virus removal | Yes | Yes |
Recovery | Poor. Sample interacts with the filter causing sample loss | Good. Disassembly of the dimeric/trimeric forms of IL-8, IL-10 and TNF-α |
Cytokine profiling | Yes | Yes |