Figure 7.

Anti-migration and -proliferation effects of β-sitosterol with or without anticancer drugs. (A,B) Migration of ovarian cancer cells following treatment with β-sitosterol in ES2 (A) and OV90 (B) cells. (C,D) Enhancement of the anti-proliferation effect of existing conventional chemotherapeutic agents by β-sitosterol. Bar graphs show the viability (percentage) of ovarian cancer cells following treatment with combinations of β-sitosterol and cisplatin or paclitaxel. Data are shown relative to the vehicle-treated controls (100%). The asterisks indicate significant differences between treated and control cells (*** p < 0.001, ** p < 0.01, and * p < 0.05). Lower-case letters indicate significant differences within the group as follows: ‘a’ compared to β-sitosterol, ‘b’ compared to cisplatin, and ‘c’ compared to paclitaxel.