Figure 6.

The spider chart for the efficiency comparison of DMF, TMF, PMF, and QC (positive control) on five markers associated with HDF damage, such as inhibition of MMP-1 mRNA expression, inhibition of MMP-1 secretion of MMP-1, stimulation of COLIA1 mRNA expression, and stimulation of COLIA1 secretion. The scores were defined from four, corresponding to the strongest effect, to 1, corresponding to the lowest effect, among the four tested samples, in addition to 0, corresponding to no effect on each factor. Abbreviations: DMF, 5,7-dimethoxyflavone; TMF, 5,7,4′-trimethoxyflavone; PMF, 3,5,7,3′,4′-pentamethoxyflavone; and QC, Quercetin.