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. 2021 Sep 30;9(10):1362. doi: 10.3390/biomedicines9101362

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Summary demonstrating that ECSW-facilitated exogenous mitochondria into ADMSCs therapy ameliorated the LV function mainly through enhancing angiogenesis, expression of cardiac stem cells/growth factors in LV myocardium, mobilization of bone marrow-derived endothelial progenitor cells into circulation, MSC differentiation and soluble angiogenesis factors. ADMSCs = adipose-derived mesenchymal stem cells; ECSW = extracorporeal shock wave; DCM = dilated cardiomyopathy; LVEF = left ventricular ejection fraction; CSC = cardiac stem cell; VEGF = vascular endothelial growth factor; TGF-ß = transforming growth factor beta.