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. 2021 Oct 5;9(10):1402. doi: 10.3390/biomedicines9101402

Table 4.

Toxicity prediction of active phytocompounds and bile component.

Phytocompounds ProTox-II
LD50(mg/kg) Hepato-Toxicity Carcino-Genecity Immuno
Toxicity		 Muta-Genicity Cyto-Toxicity
Chenodeoxycholic acid 2000
(Class 4)		 Active Inactive Inactive Inactive Inactive
Asiaticoside 4000
(Class 5)		 Inactive Inactive Active Inactive Inactive
Beta-sitosterol 890
(Class 4)		 Inactive Inactive Active Inactive Inactive
Bryophyllin A 31
(Class 2)		 Inactive Inactive Active Inactive Active
Madecassoside 1190
(Class 4)		 Active Inactive Active Inactive Inactive
Mahanimbine 4000
(Class 5)		 Inactive Inactive Active Inactive Inactive
Pennogenin 1190
(Class 4)		 Active Inactive Active Inactive Inactive
Rutin 1190
(Class 4)		 Active Inactive Active Inactive Active
Solasonine 500
(Class4)		 Inactive Inactive Active Inactive Active
Solamargine 1190
(Class 4)		 Inactive Inactive Active Inactive Active
Withaferin A 300
(Class 3)		 Inactive Inactive Active Inactive Active
Withanone 7
(Class 2)		 Inactive Inactive Active Inactive Active