Table 3.
Baseline and 1-year changes in anthropometric measurements, biochemical parameters, telomere length, and 8-OHdG plasma levels by treatment groups.
| Control Group | Intervention Group | ||||
|---|---|---|---|---|---|
| (n = 38) | (n = 31) | ||||
| Baseline | Change | Baseline | Change | p-Value | |
| Anthropometric measurements | |||||
| Body weight (kg) | 85.76 (13.08) | −0.20 (2.18) | 88.79 (14.15) | −5.51 (3.12) | <0.001 |
| BMI (kg/m2) | 32.11 (3.40) | −0.09 (0.81) | 33.07 (3.58) | −2.05 (1.14) ¥ | <0.001 |
| Waist circumference (cm) | 104.14 (10.39) | 0.03 (3.24) | 107.33 (8.44) | −7.94 (4.69) ¥ | <0.001 |
| Biochemical parameters | |||||
| Total cholesterol (mM) | 217.63 (38.56) | −5.00 (40.81) | 202.00 (34.93) | −5.68 (26.19) | 0.937 |
| LDL cholesterol (mM) | 126.56 (33.16) | 0.41 (41.12) | 116.23 (20.41) | −1.23 (19.18) | 0.853 |
| HDL cholesterol (mmol/L) | 51.82 (12.21) | −1.61 (6.10) | 46.77 (13.14) | 3.32 (5.47) | 0.001 |
| Triglycerides (mmol/L) | 224.79 (167.78) | −20.76 (105.93) | 208.10 (107.73) | −51.55 (76.07) ¥ | 0.179 |
| Glucose (mmol/L) | 101.08 (14.59) | −3.13 (12.96) | 97.58 (12.65) | −5.29 (8.47) | 0.428 |
| HbA1c (%) | 5.86 (0.50) | −0.07 (0.36) | 5.73 (0.37) | −0.11 (0.26) | 0.586 |
| Leisure-time PA (METs.min/d) | 385.02 (383.64) | −17.83 (307.89) | 302.65 (262.30) | 329.53 (403.68) ¥ | <0.001 |
| 17-point erMedDiet score | 8.00 (2.73) | 2.53 (2.78) ¥ | 6.90 (2.55) | 7.45 (2.72) ¥ | <0.001 |
| Telomere Length | 3.14 (0.51) | 0.65 (0.83) ¥ | 3.11 (0.80) | 0.67 (0.80) ¥ | 0.922 |
| 8-OHdG plasma levels | 2.84 (0.65) | 0.01 (0.56) | 2.95 (0.83) | 0.12 (0.81) | 0.528 |
Data are shown as means (SD) for continuous variables or number (%) for categorical variables for baseline characteristics. ¥ means statistical significance within a group. p values for differences between groups by ANOVA or chi-squared test, as appropriate. Telomere length and 8-OHdG plasma levels data were transformed applying log2. Abbreviations: 8-OHdG, 8-hydroxydeoxyguanosine; BMI, body mass index; erMedDiet, energy-restricted Mediterranean Diet; HbA1c, glycated haemoglobin; PA, physical activity.