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. 2021 Oct 7;11(10):1477. doi: 10.3390/biom11101477

Figure 2.

Figure 2

Downregulation of PPARγ expression was normalized by GYY treatment in diabetic kidney and MCs under HG condition. Protein was extracted from (A) saline- or GYY-treated kidneys from WT and Akita mice and (B) untreated or GYY-treated mouse MCs in NG or HG condition and analyzed for PPARγ expression by Western blot. The expression of PPARγ was normalized with GAPDH. The bar graphs represent the mean fold change ± SD vs. WT + Saline or NG. n = 6/group or 3 independent experiments, * p  <  0.05 vs. WT + Saline or NG, † p  <  0.05 vs. Akita + Saline or HG.