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CRE decreased inflammatory cytokines and OVA-specific IgE in animals with asthma. (a) IL-4, (b) IL-5, (c) IL-13, (d) OVA-specific IgE. NC: PBS treatment and PBS challenge; OVA: PBS treatment and OVA challenge; DEX: dexamethasone (2 mg/kg) treatment and OVA challenge; CRE30 and CRE100: CRE (30 mg/kg and 100 mg/kg, respectively) and OVA challenge. The values are shown as the mean ± SD (n = 5–7). ## p < 0.01 versus NC; *, ** p < 0.05 and 0.01 versus OVA.
