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. 2021 Oct 15;10(10):1626. doi: 10.3390/antiox10101626

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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CRE increased the expression of Nrf2/HO-1/NQO1 in animals with asthma. (a) The expression of Nrf2/HO-1/NQO1, (b) relative expression, (c) immunohistochemistry for HO-1. The black box is enlarged and shown in the lower histological figure of (c). NC: PBS treatment and PBS challenge; OVA: PBS treatment and OVA challenge; DEX: dexamethasone (2 mg/kg) treatment and OVA challenge; CRE30 and CRE100: CRE (30 mg/kg and 100 mg/kg, respectively) and OVA challenge. The values are shown as the mean ± SD (n = 5). ^## p < 0.01 versus NC; ** p < 0.01 versus OVA.