Skip to main content
. 2021 Sep 30;11(10):1434. doi: 10.3390/biom11101434

Figure 5.

Figure 5

Quantification of AAA histopathological features in elastase-infused normocholesterolemic WT and hypercholesterolemic ApoE−/− female mice (n = 7 and 8 mice in WT and ApoE−/− mouse groups, respectively). (A–C): Media and 95% confidence interval (CI) of the scores for medial elastin (A) and smooth muscle cell (SMC) (B) destruction as well as CD68-positive macrophage accumulation (C). Scores I to IV represent mild to severe destruction. (D): Mean and 95% CI for CD4+ T cells (E) per aortic cross-section (ACS). (E,F): Media and 95% CI for CD8+ T cells (E) B220+ B cells (F) per ACS. (G): Mean and 95% CI of CD31+ neovessels per ACS. Nonparametric Mann–Whitney test (A–C,E,F) or Student’s t-test (D,G) indicated no significance difference between two groups.