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. 2021 Oct 4;9(10):1391. doi: 10.3390/biomedicines9101391

Figure 10.

Figure 10

ECSW therapy suppressed the protein levels of inflammatory signalings in rat urinary bladder by day 42 after ketamine administration. (A) Protein expression of Toll-like receptor (TLR)-2, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (B) Protein expression of TLR-4, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (C) Protein expression of MyD88, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (D) Protein expression of TRAF6, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (E) Protein expression of p-IKB-α, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (F) Protein expression of NF-κB, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (G) Protein expression of TNF-α, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (H) Protein expression of interleukin (IL)-1ß, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (I) Protein expression of MMP-9, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (J) Protein expression of COX-2, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. (K) Protein expression of and iNOS, * vs. other groups with different symbols (†, ‡, §), p < 0.0001. All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test (n = 6 for each group). Symbols (*, †, ‡, §) indicate significance (at 0.05 level). ECSW = extracorporeal shock wave.