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Tyrosinase inhibitory activity of the methanolic fruit extracts (10 μg/mL) obtained from different spices of genus Piper, piperine (10 μg/mL) and kojic acid (10 μg/mL). Data are presented as percentage of tyrosinase activity in comparison to solvent (DMSO) control, set at 100%. Each bar represents the mean ± S.D. of three determinations; * p < 0.05; ** p < 0.01; *** p < 0.001 vs. control.
