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Proposed mechanism of action of apigenin in metabolic syndrome. CAT: catalase; CD36: cluster determinant 36; CD38: cluster of differentiation 38; GPX: glutathione peroxidase; GSH: glutathione; H2O2: hydrogen peroxide; O2−: superoxide anion; OH·: hydroxyl radical; SIRT1: sirtuin-1; SOD: superoxide dismutase; STAT3: signal transducer and activator of transcription 3; TXNRD: thioredoxin reductase.
