Table 6.
CT-derived PAFV/VATA and coronary atherosclerosis in Chinese middle aged and elderly patients.
| PAFV and CAD-CA | CAD-CA Cases/Total | Prevalence of CAD-CA, OR (95% CI) | ||
|---|---|---|---|---|
|
| ||||
| Model 1 | Model 2 | Model 3 | ||
|
| ||||
| Logistic Regression | 429/750 | 1.03 (1.01–1.05)** | 1.02 (1.00–1.04)* | 1.02 (1.00–1.04) |
| Per quartile* | ||||
| Q1 | 71/188 | Reference | Reference | Reference |
| Q2 | 105/187 | 1.76 (1.13–2.71)^ | 1.68 (1.03–2.65)^ | 1.33 (0.93–2.49) |
| Q3 | 119/187 | 1.93 (1.22–3.04)^^ | 1.74 (1.06–2.87)^ | 1.65 (1.00–2.73) |
| Q4 | 134/188 | 2.21 (1.33–3.68)^^ | 1.90 (1.07–3.37)^ | 1.73 (1.00–3.10)^ |
| CADmsCA Cases/Total | Prevalence of CAD-msCA, OR (95% CI) | |||
|
| ||||
| Model 1 | Model 2 | Model 3 | ||
|
| ||||
| Logistic Regression | 176/750 | 1.02 (1.01–1.04) | 1.02 (1.00–1.04) | 1.01 (0.99–1.03) |
| Per quartile* | ||||
| Q1 | 16/188 | Reference | Reference | Reference |
| Q2 | 37/187 | 2.19 (1.14–4.20)^ | 2.01 (1.03–3.93)^ | 1.98 (0.99–3.86) |
| Q3 | 53/187 | 2.77 (1.47–5.23)^^ | 2.18 (1.08–4.40)^ | 2.03 (1.00–4.12) |
| Q4 | 70/188 | 3.15 (1.64–6.05)^^ | 2.26 (1.17–4.42)^ | 2.20 (1.13–4.29)^ |
| VATA and CAD | CAD-CA Cases/Total | Prevalence of CAD-CA, OR (95% CI) | ||
|
| ||||
| Model 1 | Model 2 | Model 3 | ||
|
| ||||
| Logistic Regression | 429/750 | 1.00 (1.00–1.01)^ | 1.00 (0.99–1.01) | 1.00 (0.99–1.01) |
| Per quartile* | ||||
| Q1 | 84/188 | Reference | Reference | Reference |
| Q2 | 97/187 | 1.33 (0.86–2.06) | 1.13 (0.70–1.84) | 1.07 (0.66–1.74) |
| Q3 | 129/187 | 2.27 (1.64–3.84)^^ | 1.96 (1.00–3.04) | 1.73 (0.98–3.00) |
| Q4 | 119/188 | 1.90 (1.01–2.85)^ | 1.75 (0.98–2.50) | 1.30 (0.84–2.04) |
| CADmsCA Cases/Total | Incidence of CAD-msCA, OR (95% CI) | |||
|
| ||||
| Model 1 | Model 2 | Model 3 | ||
|
| ||||
| Logistic Regression | 176/750 | 1.01 (1.00–1.02)^^ | 1.01 (1.00–1.02)^ | 1.00 (1.00–1.01)^ |
| Per quartile* | ||||
| Q1 | 23/188 | Reference | Reference | Reference |
| Q2 | 34/187 | 1.63 (0.88–2.98) | 1.29 (0.67–2.47) | 1.26 (0.65–2.43) |
| Q3 | 53/187 | 2.72 (1.54–4.81)^^ | 1.99 (1.04–3.79)^ | 1.94 (1.00–3.75)^ |
| Q4 | 67/188 | 3.04 (1.74–5.32)^^ | 2.23 (1.14–4.39)^ | 2.07 (1.01–4.27)^ |
Model 1: Adjusted for age and gender.
Model 2: As for model 1, additionally adjusted for BMI, current smoking, hypertension, diabetes, plasma low-density lipoprotein cholesterol and high-density lipoprotein cholesterol.
Model 3: As for model 2, additionally adjusted for waist circumference.
* The ranges of PAFV per quartile were as follows: Q1: 4.2–10.3cm3. Q2: 10.4–15.2 cm3. Q3: 15.3–22.7 cm3. Q4: 22.8–51.5 cm3, and VATA Q1: 21.8–89.2 cm3. Q2: 89.4–121.4 cm3. Q3: 121.7–156.6 cm3. Q4: 156.8–298.8 cm3.
Abbreviations: CT, computed tomography; CAD-CA, coronary artery atherosclerosis; CAD-msCA, moderate to severe coronary artery atherosclerosis; OR, odd ratio; CI, confidence interval.
^: p < 0.05, ^^: p < 0.01 in logistic regression analysis.