5-FU	5-Fluorouracil
ACC	Adenoid Cystic Carcinoma
ACL	Lung Adenocarcinoma
ADAM	A Disintegrin and Metalloproteinase
AIF	Apoptosis-Inducing Factor
ALDH	Aldehyde Dehydrogenase
ALL	Acute Lymphoblastic Leukemia
AML	Acute Myeloid Leukemia
ANK	Ankyrin Repeats
APP	Amyloid Precursor Proteins
ARA-C	Cytarabine
ASCL1	Achaete-Scute Homolog 1
ATP	Adenosine Triphosphate
B-ALL	B-cell Acute Lymphoblastic Leukemia
BBB	Blood−Brain Barrier
BBC3	BCL-Binding Component 3
BCL	B-cell lymphoma
BMF	BCL2-Modifying Factor
BRD4	Bromodomain-containing protein 4
BTK	Bruton Tyrosine Kinase
CBF1	C-repeat/DRE-Binding Factor 1
CD	Cluster of Differentiation
CI	Combination Index
CLL	Chronic Lymphocytic Leukemia
CNS	Central Nervous System
CRC	Colorectal Cancer
CR	Complete Response
CSC	Cancer Stem Cell
CSL	CBF-1/RBP-Jκ/Suppressor of Hairless and Lag-1
CT	Clinical Trial
CtBP	C-Terminal Binding Protein
CtIP	CtBP Interacting Protein
DAC	5-aza-2′deoxycytidine
DGC	Diffuse Gastric Cancer
DHFR	Dihydrofolate Reductase
DLK	Delta-like Homolog
DLL	Delta-like Ligand
DN	Double Negative
DNMT	DNA Methyltransferase
DSL	Delta/Serrate/Lag2 ligands
EAC	Esophageal Adenocarcinoma
EC	Endothelial Cells
EGF	Epidermal Growth Factor
EGFR	Epidermal Growth Factor Receptor
EMT	Epithelial-Mesenchymal Transition
ER	Endoplasmic Reticulum
ERα+	Estrogen Receptor α-Positive
ERK	Extracellular Signal-Regulated Kinase
ESCC	Esophagus Squamous Cell Carcinoma
EZH2	Enhancer of Zeste Homolog 2
FOLFIRI	Folinic Acid/5-FU/Irinotecan
FBXW7	F-Box and WD Repeat Domain Containing 7
FDA	Food and Drug Administration
FGFR	Fibroblast Growth Factor Receptor
GBM	Glioblastoma Multiforme
GCT	Gastric Carcinoid Tumor
GI	Gastrointestinal
GR	Glucocorticoid Receptor
GS	Gamma-Secretase Complex
GSC	Glioma Stem-Like Cells
GSI	Gamma-Secretase Inhibitor
GSK-3	Glycogen Synthase Kinase-3
H	Histone
HAT	Histone Acetyltransferase
HCC	Hepatocellular Carcinoma
HD	Heterodimerization Domain
HDAC	Histone Deacetylase
HER	Human Epidermal Growth Factor Receptor
HES	Hairy/Enhancer of Split
HIF	Hypoxia Inducible Factor
HMT	Histone Methyltransferase
HNSCC	Head and Neck Squamous Cell Carcinoma
HNK	Honokiol
HPV	Human Papillomavirus
HSC	Hematopoietic Stem Cells
IC50	Half-Inhibitory Concentration
IGF1R	Insulin-like Growth Factor 1
IKK	Inhibitor of Nuclear Factor-κB (IκB) Kinase
IL	Interleukin
IMR-1	Inhibitor of Mastermind Recruitment-1
IXN	Isoxanthohumol
JMJD3	Jumonji Domain-Containing Protein 3
KDM	Lysine Demethylase
KMT	Lysine Methyltransferase
LCNEC	Large-Cell Neuroendocrine Carcinoma
LIC	Leukemia-Initiating Cells
LiCl	Lithium Chloride
LNR	Lin12-Notch Repeats
LSC	Leukemia Stem Cells
LSCC	Lung Squamous Cell Carcinoma
LSD1	Lysine Demethylase 1
mAb	Monoclonal Antibody
MAGP	Microfibril-Associated Glycoprotein
MAM	Mastermind
MAML	Mastermind-like
MAPK	Mitogen-Activated Protein Kinase
MCL1	Myeloid Cell Leukemia Sequence 1
MDR	Multidrug Resistance
miR	MicroRNA
MM	Multiple Myeloma
MMP	Matrix Metallopeptidase
MRI	Magnetic Resonance Imaging
MRP1	Multidrug-Resistance-Associated Protein-1
MTC	Medullary Thyroid Cancer
mTOR	Mammalian Target of Rapamycin
NAC	N-Acetylcysteine
N1IC	Notch1 Intracellular Domain
N2IC	Notch2 Intracellular Domain
N3IC	Notch3 Intracellular Domain
N4IC	Notch4 Intracellular Domain
NEC	Notch Extracellular Domain
NET	Neuroendocrine Tumor
NEXT	Notch Extracellular Truncation
NF-κB	Nuclear Factor κB
NHD	Notch Heterodimerization Domain
NIC	Notch Intracellular Domain
NR2F6	Nuclear Receptor Subfamily Group F Member 6
NRF2	Nuclear Factor Erythroid 2-Related Factor 2
NRR	Negative Regulatory Region
NSC	Neural Stem Cells
NSCLC	Non-Small-Cell Lung Cancer
NTC	Notch Transcription Complex
NTM	Notch Transmembrane−intracellular Fragment
OR	Objective Response
ORR	Objective Response Rate
OS	Overall Survival
PARP	Poly (ADP-Ribose) Polymerase
PD	Progressive Disease
PDAC	Pancreatic Ductal Adenocarcinoma
PDGF	Platelet-Derived Growth Factor
PDX	Patient-Derived Xenograft
PEST	Proline (P)/Glutamic Acid (E)/Serine (S)/Threonine (T)-Rich Motif
PFKFB2	6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 2
PFS	Progression-Free Survival
PHF8	Histone Lysine De-methylase PHF8
PI3K	Phosphatidylinositol-3-kinase
Pofut1	O-fucosyltransferase1
PR	Partial Response
PRC2	Polycomb-Repressive Complex 2
PSEN	Presenilin
PTEN	Phosphatase and Tension Homolog Deleted on Chromosome 10
PTMs	Post-Translational Modifications
RAM	RBP-jκ Associated Molecule
RIN1	RBP-jκ INhibitor-1
RISC	RNA-Induced Silencing Complex
ROS	Reactive Oxygen Species
Rova-T	Rovalpituzumab Tesirine
RBP-jκ	Recombination Signal Binding Protein for Immunoglobulin Kappa J Region
RCT	Randomized Clinical Trial
RT	Radiotherapy
SCC	Squamous Cell Carcinoma
SCFFbxw7	S-phase-Kinase-Associated Protein1(SKP1) Cullin1(CUL1)-F-box
SCLC	Small-Cell Lung Cancer
SD	Stable Disease
SERCA	Sarco(endo)plasmic Reticulum Ca+2 ATPase
SHARP	SMRT/HDAC1-Associated Repressor Protein
siRNA	Silencing RNA
SSCC	Skin Squamous Cell Carcinoma
STAT	SRA Taxonomy Analysis Tool
TAD	Transactivation Domain
T-ALL	T-cell Acute Lymphoblastic Leukemia
TCR	T-cell Receptor
TF	Transcription Factor
TG	Thapsigargin
TGF	Transforming Growth Factor
T-ISC	Tumor-Initiating Stem Cells
TMZ	Temozolomide
TNBC	Triple-Negative Breast Cancer
TS	Thymidylate Synthase
UTX	Ubiquitously Transcribed Tetratricopeptide Repeat X-linked Protein
VEGF	Vascular Endothelial Growth Factor
VEGFR	Vascular Endothelial Growth Factor Receptor
VPA	Valproic Acid
WA	Withaferin A
WT	Wild-Type
XN	Xanthohumol
ZEB1	Zinc Finger E-Box Binding Homeobox 1