Figure 2.

Evaluation of MVD in MITO16A population and its correlation with selected angiogenesis-related genes. (A). Representative picture showing CD31-positive intratumoral microvessels (arrow) and CD31-positive entities associated with α-SMA positive cells (arrowhead) (magnification 40×, scale bar 100 μm). The microvessel density (MVD) and the αSMA+ microvessel density (αSMA + MVD) were expressed as mean number of vessel per mm². (B). Distribution of CD31 and α-SMA expression in the analyzed samples. On the left, the distribution of α-SMA + MVD/MVD ratio is shown. (C). Pairwise distribution of biomarkers. The correlogram plot reports the Kendall’s tau values. On the right is shown the color scale used.