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. 2021 Oct 2;10(10):2640. doi: 10.3390/cells10102640

Figure 8.

Figure 8

BMP-7 reduced cardiac infiltrated inflammatory cells, hypertrophy, interstitial, and vascular fibrosis in the diabetic heart. (A) Hematoxylin and Eosin staining (H&E) of heart sections showing inflammatory cells in images (a–c) and enlarged (d–f); hypertrophy in images (g–i) and enlarged (j–l) in all 3 groups. (B) Representative photomicrographs of Masson’s trichrome staining performed on heart sections to assess interstitial (a–c), vascular (d–f) fibrosis, and the number of blood vessels (g–i) in all 3 groups. (C–G) Quantitative analysis of the number of inflammatory cells (C) and cardiomyocyte cell diameter area (hypertrophy) (D), interstitial fibrosis (E), vascular fibrosis (F), and the number of blood vessels (G) in all groups. Statistical analysis was performed using One-Way ANOVA, which was followed by the Tukey test. Images taken at 40×; Error bars = mean ± S.E.M. * p < 0.05, *** p < 0.001; Scale bar = 100 µm; n = 16/group.