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Model III-based predicted survival curves of patients diagnosed in 2014 (left) and 2016 (right) with the following characteristics: 80-year-old male, with 1 × elevated LDH, ECOG PS of ≥2 with 0–2 organ sites, no liver or brain metastases, BRAF wild-type tumor, who would be treated in the centers with the highest, lowest, and average HR in the dataset. HR = hazard ratio.
