Table 1.
Patient and tumor characteristics of patients diagnosed between 2013 and 2017. If ≥5% of data are missing for a variable, this is indicated by the category “unknown”.
| Variable | Level | Total (N) = 3820 |
|---|---|---|
| Age (median (range)) | 64 (18–97) | |
| Gender (%) | Male | 2254 (59.0) |
| Female | 1565 (41.0) | |
| ECOG PS (%) | 0–1 | 2832 (84.8) |
| ≥2 | 507 (15.2) | |
| Unknown | 481 (12.6) | |
| Stage (%) | IIIc unresectable | 190 (5.0) |
| IV-M1a | 297 (7.8) | |
| IV-M1b | 397 (10.5) | |
| IV-M1c | 2903 (76.7) | |
| LDH (%) | Normal | 2215 (63.1) |
| 1–2 × ULN | 816 (23.2) | |
| >2 × ULN | 479 (13.6) | |
| Unknown/not determined | 310 (8.1) | |
| Brain metastases (%) | No | 2672 (71.5) |
| Yes, asymptomatic | 334 (8.9) | |
| Yes, symptomatic | 730 (19.5) | |
| Liver metastases (%) | No | 2667 (70.9) |
| Yes | 1094 (29.1) | |
| Organ sites (%) | <3 | 2047 (53.6) |
| ≥3 | 1773 (46.4) | |
| BRAFV600 mutation (%) | Wild-type | 1741 (45.6) |
| Mutant | 2079 (54.4) |