Figure 1.

Effect of resveratrol on the basal cAMP cellular level in control and parkin-mutant fibroblasts. Basal cyclic adenosine monophosphate (cAMP) cellular level, expressed as pmol/mg protein, in control (open bar) and parkin-mutant (black bar) fibroblasts exposed to either vehicle (DMSO) or 25 μM resveratrol (RSV) for 30 min. The values represent the means ± SEM from 3 independent experiments under each condition. The significance was determined by two-way ANOVA with Tukey post hoc; *, p ˂ 0.01; **, p ˂ 0.001; ***, p ˂ 0.0005. For more details, see Materials and Methods.