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Macrophage phenotype associates with collagen volume fraction. Pearson’s correlations for (A) M1/M2 ratio; (B) M1 (Mac-2+CD86+) macrophages; and (C) M2 (CD206+) macrophages with collagen volume fraction in hearts from Cont, Leprdb/db + saline, and Leprdb/db + SP mice. Individual data points for all groups were included and analysed by Pearson correlation co-efficient.
