Table 2.
Predictive performance of features in different subsets of nodes.
| Data | Specificity | Sensitivity | NPV | PPV | Threshold |
|---|---|---|---|---|---|
| all nodes | |||||
| p. vascularization | 0.84 (0.77–0.90) | 0.87 (0.80–0.93) | 0.88 (0.80–0.94) | 0.83 (0.74–0.90) | |
| absent fatty hilum | 0.84 (0.77–0.90) | 0.84 (0.77–0.90) | 0.86 (0.76–0.92) | 0.82 (0.72–0.90) | |
| short axis diameter | 0.45 (0.19–0.81) | 0.88 (0.80–0.95) | 0.82 (0.59–0.89) | 0.59 (0.45–0.82) | 6.5 1 |
| short axis diameter | 0.25 (0.17–0.35) | 0.95 (0.89–0.98) | 0.84 (0.68–0.94) | 0.53 (0.43–0.62) | 6.0 2 |
| resistive index | 0.54 (0.34–0.70) | 0.88 (0.78–0.93) | 0.85 (0.72–0.92) | 0.61 (0.50–0.74) | 0.705 1 |
| S/L ratio 3 | 0.45 (0.37–0.53) | 0.88 (0.82–0.93) | 0.82 (0.69–0.90) | 0.59 (0.49–0.67) | 0.5 |
| cN0 patients | |||||
| p. vascularization | 0.79 (0.70–0.88) | 0.94 (0.56–1.00) | 0.98 (0.92–1.00) | 0.50 (0.27–0.71) | |
| asent fatty hilum | 0.82 (0.73–0.89) | 0.82 (0.60–1.00) | 0.96 (0.89–0.99) | 0.50 (0.24–0.72) | |
| short axis diameter | 0.26 (0.15–0.55) | 0.94 (0.57–1.00) | 0.95 (0.59–1.00) | 0.22 (0.11–0.38) | 5.5 1 |
| short axis diameter | 0.05 (0.01–0.11) | 1.00 (0.80–1.00) * | 1.00 (0.40–1.00) * | 0.19 (0.09–0.32) | 4.0 2 |
| restistive index | 0.25 (0.15–0.36) * | 1.00 (0.77–1.00) * | 1.00 (0.81–1.00) * | 0.20 (0.06–0.31) | 0.615 1 |
| S/L ratio 3 | 0.46 (0.36–0.56) | 0.88 (0.71–1.00) | 0.95 (0.82–1.00) | 0.26 (0.14–0.42) | 0.5 |
| absent fatty hilum | |||||
| p. vascularization | 0.71 (0.45–0.89) | 0.92 (0.85–0.97) | 0.67 (0.38–0.85) | 0.94 (0.86–0.98) | |
| cN0 and absent fatty hilum absent | |||||
| p. vascularization | 0.64 (0.36–0.88) | 0.93 (0.50–1.00) | 0.90 (0.55–1.00) * | 0.72 (0.40–0.92) | |
|
short axis diameter
mm ≤ 6 |
|||||
| p. vascularization | 0.90 (0.79–0.96) | 0.73 (0.33–0.93) | 0.94 (0.82–0.98) | 0.62 (0.30–0.86) | |
| absent fatty hilum | 0.80 (0.67–0.89) | 0.91 (0.00–1.00) | 0.98 (0.86–1.00) | 0.50 (0.23–0.72) | |
| resistive index | 0.26 (0.00–0.58) | 0.80 (0.38–1.00) | 0.86 (0.57–0.98) * | 0.19 (0.07–0.30) | 0.615 1 |
| S/L ratio 3 | 0.61 (0.49–0.73) | 0.82 (0.40–1.00) | 0.94 (0.79–1.00) | 0.32 (0.16–0.52) | 0.5 |
The given confidence intervals are 95% bias-corrected accelerated bootstrap confidence intervals when possible. * 95% binomial proportion confidence interval. 1 threshold determined such that sensitivity ≥ sensitivity for peripheral vascularization. 2 threshold based on the literature. 3 ratio short axis diameter / long axis diameter.