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. 2021 Oct 1;10(10):2628. doi: 10.3390/cells10102628

Figure 2.

Figure 2

Graphical representation of a tripartite synapse where the following neurometabolic pathways involved in depression and possibly affected by Kir4.1 dysfunction are schematically illustrated: (A) Serotonergic transmission (B) astrocyte-mediated K+ siphoning, glutamate reuptake, and BDNF secretion (C) glutamatergic transmission.