Table 1.

Kir4.1 channel expression changes in depression.

Reference	Model	Brain Areas	Kir4.1 Expression
Medina et al., 2016 [38]	Post-mortem study on brain samples from patients with depression	Hippocampus	↓ Kir4.1
Cui et al., 2018 [37] and Yang et al., 2018 [54]	Rodent models of depression (cLH rat and LPS-treated rat)	Lateral Habenula	↑ Kir4.1
Xiong et al., 2019 [39]	Post-mortem study on brain samples from patients with depression	Parietal cortex	↑ Kir4.1
Xiong et al., 2019 [55]	Rodent models of depression (CSDS model)	Prefrontal cortex, nucleus accumbens septi and hippocampus	No change

cLH: congenitally learned helpless rat, LPS: lipopolysaccharide, CSDS: chronic social defeat stress.