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Schematic representation of one of the forms of emperipolesis, suicidal emperipolesis, which is formed by hepatocytes and autoreactive T lymphocytes. 1. The T lymphocyte is activated and enters the hepatocyte’s cytoplasm; 2. The lymphocyte is entirely engulfed within the hepatocyte’s cytoplasm; 3. The lymphocyte is digested within a lysosome.
