5-FU |
5-fluorouracil |
ADAM17 |
Adisintegrin and metalloproteinase 17 |
ALD |
Alcoholic liver disease |
ALC |
Alcoholic liver cirrhosis |
APC |
Antigen presenting cells |
ARG1 |
Arginase 1 |
ATRA |
All-trans retinoic acid |
CCL |
Chemokine (C-C motif) ligand |
CCR |
CC motif chemokine receptors |
CIK |
Cytokine-induced killer |
COX2 |
Cyclooxygenase 2 |
CSF1/M-CSF |
Colony-stimulating factor 1 |
CSF1R |
Colony-stimulating factor 1 receptor |
CXCL |
C-X-C motif ligand |
DCs |
Dendritic cells |
eMDSCs |
Early MDSCs |
ENTPD2 |
Ectonucleoside triphosphate diphosphohydrolase 2 |
Gem |
Gemcitabine |
GMP |
Gemcitabine monophosphate |
HAIC |
Hepatic arterial infusion chemotherapy |
HBV |
Hepatitis B virus |
HCC |
Hepatocellular carcinoma |
HCV |
Hepatitis C virus |
HDACIs |
Histone deacetylase inhibitors |
HSCs |
Hematopoietic stem cells |
ICIs |
Immune-checkpoint inhibitors |
IDO |
Indoleamine2,3-dioxygenase1 |
IL |
Multiple interleukins |
IMCs |
Immature myeloid cells |
LCP |
Lipid-coated calcium phosphate |
LN |
L-selectin lymph node |
LOX-1 |
Lectin-type oxidized LDL receptor 1 |
MDSCs |
Myeloid-derived suppressor cells |
M-MDSCs |
Monocytic MDSCs |
MPO |
Myeloperoxidase |
NAFLD |
Non-alcoholic fatty liver disease |
NO |
Nitric oxide |
NOX2 |
NADPH oxidase |
PDE5 |
Phosphodiesterase 5 |
PGE2 |
Prostaglandin E2 |
PMN-MDSCs |
Polymorphonuclear MDSCs |
RIPK3 |
Receptor-interacting protein kinase 3 |
RNS |
Reactive nitrogen species |
ROS |
Reactive oxygen |
TAFs |
Tumor-associated fibroblasts |
TAM2 |
M2-polarized tumor-associated macrophages |
TLR2 |
Toll-like receptors 2 |
TIM3 |
T-cells immunoglobulin and mucin domain-containing protein 3 |
TIME |
Tumor immune microenvironment |
TKIs |
Tyrosine kinase inhibitors |
TNF-a |
Tumor necrosis factor-a |
TRAIL-Rs |
TNF-related apoptosis-induced ligand receptors |
Tregs |
Regulatory T cells |