Table 1.
Studies comparing data about lymph node metastasis in thymic tumors over the last 20 years.
| Author | Year | Country | P/R | N pts | Intentional Lymphadenectomy | n LN Dissected (Mean) | Type of Tumor (%) | Lymph Node Metastasis (%) | Metastatic Stations (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T | TC | NETT | Overall | T | TC | NETT | N1 | N2 | |||||||
| Kondo [3] | 2003 | Japan | R | 1320 | No | - | 82.8 | 14.1 | 3.1 | 6.7 | 1.8 | 26.8 | 27.5 | - | - |
| Park [4] | 2013 | Korea | R | 29 | Yes | 9.4 | - | 100 | - | 20.8 | - | 20.8 | - | - | - |
| Weissferdt [20] | 2012 | USA | R | 33 | Yes | - | - | 100 | - | 37 | - | 37 | - | 16.7 | 20 |
| Weksler [6] | 2015 | USA | R | 229 | No | 3 | - | 76.9 | 23.1 | 40.2 | - | 33.5 | 62.3 | - | - |
| Weksler [7] | 2015 | USA | R | 442 | No | 2 | 100 | - | - | 13.3 | 13.3 | - | - | - | - |
| Hwang [8] | 2016 | Korea | R | 131 | Yes | 10.3 | 75.6 | 24.4 | - | 9.9 | 5.1 | 25 | - | 4.6 | 5.4 |
| Gu [2] | 2017 | China | R | 1617 | No | - | 81 | 16.4 | 2.6 | 2.2 | 0.5 | 7.9 | 16.7 | - | - |
| Zhao [21] | 2017 | China | R | 116 | Yes | 2.3 (TC) 1.8 (NETT) |
- | 81.8 | 18.1 | 53.4 | - | 48.4 | 76.2 | 50 | 35.5 |
| Fang [22] | 2018 | China | P | 275 | Yes | 4.9 | 88.4 | 8.7 | 2.9 | 5.5 | 2.1 | 25 | 50 | 4.7 | 2.9 |
| Hwang [23] | 2018 | Korea | R | 446 | Yes | 8.9 | 66.8 | 33.2 | - | 15.0 | 6.7 | 31.8 | - | 9.6 | 5.4 |
| Wen [24] | 2018 | China | R | 3947 | No | - | 70.6 | 21.9 | 7.4 | 6.1 | 11.1 | 33.0 | 57.0 | - | - |
| Cheufou [25] | 2019 | Germany | R | 53 | No | 3.5 | - | 81.1 | 18.9 | 30.2 | - | 24.5 | 5.6 | 20.8 | 9.4 |
| Song [26] | 2019 | China | R | 363 | No | - | - | 66.3 | 33.7 | 34.3 | - | - | - | - | - |
| Wang [27] | 2020 | USA | R | 398 | Yes | 1–3 (46%) >4 (47%) |
- | 78.6 | 21.4 | 36.2 | - | 30 | 58.8 | - | - |
| Clermidy [28] | 2021 | France | R | 54 | Yes | 3.9 | 100 | - | - | 5.6 | 5.6 | - | - | 0 | 6.1 |
P/R: prospective/retrospective; T: thymoma; TC: thymic carcinoma; NETT: thymic neuroendocrine tumor; LN: lymph node.