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Phagocytic capacities of microglia and infiltrating monocytes in the early phase of MS: Yamasaki et al. reported that at the onset of EAE, the ratio of microglia to monocytes contacting demyelinated axons is about 1:2, monocytes locating closer to axons than microglia [15]. The amount of myelin phagocytosis per cell is higher in microglia than monocytes [76,77], but monocytes as a whole (i.e., per animal) phagocytose more myelin.
