Table 2.
List of nanocarriers/NPs for the delivery of potential therapeutic miRNAs for UM.
| Potential Therapeutic miRNA for UM | Nanocarriers/NPs | Targeting Cells | Ref. |
|---|---|---|---|
| Anti-miR-21 oligonucleotide | Aptamer-decorated PEGylated PLGA NPs | Ovarian cancers | [104] |
| Acid-triggered charge-reversible graphene-based multilayer polymers | Triple-negative breast cancer | [105] | |
| GNPs | Breast cancer cells | [106] | |
| Chlorotoxin-coupled stable nucleic acid lipid NPs | Glioblastoma | [107] | |
| 3WJ-based RNA NPs | Glioblastoma | [108] | |
| Let-7b | HA-G5 PAMAM dendrimer | CD44+ non-small-cell lung cancer cells | [109] |
| Cationic liposomes | Neuroblastoma | [110] | |
| miR-17 | DOTAP-modified PLGA lipid–polymer hybrid NPs | Bronchial epithelial cells | [111] |
| miR-124a | Disulfide-linked PEI NPs | Neuron cells | [86] |
| miR-142-3p | G5 PAMAM dendrimers | Myeloid cells | [112] |
| miR-145 | Micelles | Vascular smooth muscle cells | [113] |
| Disulfide cross-linked micelles | Colon cancer cells | [114] | |
| Nanocapsules | Colorectal cancer cells | [115] | |
| PLGA NPs | Vascular smooth muscle cells | [116] | |
| Chitosan-thiolated dextran NPs | Cancer cells | [117,118] | |
| Magnetic nanoformulation | Pancreatic cancer | [119] | |
| Polyarginine-disulfide-linked PEI NPs | Prostate cancer | [120] | |
| GNPs | Prostate and breast cancer cells | [121] | |
| HA-PLGA/PEI with miR-145 expression plasmid | Colon carcinoma | [122] | |
| Chitosan polyplex NPs with miR-145 expression plasmid | MCF-7 | [123] | |
| miR-182 | PEGylated GNP nanogel | Metastatic breast cancer | [124] |
| PEGylated GNPs | Glioblastoma | [125] | |
| miR-34a, miR-137, miR-144 and miR-182 | GNPs | UM cells | [126] |