FIG 7.

Salmonella coinfection does not limit H. pylori iron availability. (A) Gastric expression of lipocalin-2 was greater in H. pylori- and Salmonella-coinfected mice than in those infected with H. pylori alone. Hepcidin expression was decreased by H. pylori infection with or without Salmonella coinfection. (B) Fold change expression of fur relative to input PMSS1 was higher in low-passage-number H. pylori isolated from mice fed an iron-deficient than in iron-replete controls. (C) Fold change expression of fur relative to input PMSS1 from H. pylori isolated 8 weeks p.i. and cocultured with AGS cells was not affected by Salmonella coinfection. Bars indicate means ± SEMs. *, P < 0.05.