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. 2021 Oct 7;10(10):2684. doi: 10.3390/cells10102684
Variables No. Median Survival Time (Month) 5-Year Survival (%)÷(CI) Univariate Multivariate
HR p-Value HR p-Value
Sex Male
Female
1684
1333
-÷- 62 (59–64) Reference 0.9198 Reference 0.1549
62 (59–64) 1.01 (0.89–1.13) 0.92 (0.81–1.03)
Location Extremity 2291 - 68 (66–70) Reference <0.0001÷ Reference <0.0001
Axial 403 25 36 (31–41) 2.72 (2.33–3.17) 0.91 (1.62–2.24)
Elsewhere 323 54 49 (43–55) 1.77 (1.48–2.12) 1.31 (1.09–1.58)
Extent of
disease÷(since 2006)
Localized 910 - 73 (69–76) Reference <0.0001 Reference <0.0001
Metastasis 644 41 44 (40–48) 2.60 (2.19–3.10) 2.40 (2.03–2.84)
Unknown 413 - 71 (66–75) 0.98 (0.78–1.24) 1.57 (1.34–1.83)
Age group Young children 214 - 78 (71–83) Reference <0.0001 Reference <0.0001
Pubertal children 610 - 73 (70–77) 1.24 (0.90–1.70) 1.22 (0.89–1.67)
AYA 1307 - 68 (65–71) 1.47 (1.09–1.98) 1.35 (1.00–1.82)
Adults 608 44 47 (43–51) 3.06 (2.64–4.16) 2.55 (1.87–3.47)
Elderly 278 20 25 (20–31) 5.88 (4.28–8.08) 4.69 (3.39–6.49)