Table 1.
Clinical and microbiological characteristics of reported cases.
| PATIENT 1 Hospitalisation 25–31 May 2020 |
PATIENT 2 Hospitalisation 27.05–29 May 2020 |
|
|---|---|---|
| Sex | Male | Male |
| Age | 71 | 64 |
| Social status | Homeless | Homeless |
| Comorbidities | Atrial fibrillation | HIV-positive Renal insufficiency |
| Symptoms on admission | Cough, weakness, malaise, coughing up sputum | No data |
| TB | ||
| Medical history | 1981—pulmonary tuberculosis | December 2018—pulmonary tuberculosis February 2019—urogenital tuberculosis |
| Chest X-ray, CT | (28 May 2020) Lesions suggesting pulmonary TB | No data |
| Bacteriological assay | (29 May 2020) Sputum AFB (+++)—MTBC culture | Sputum AFB (+)—MTBC culture Urine AFB (+++)—MTBC culture |
| Genetic assay | (29 May 2020) GeneXpert Sputum (+) |
(19 June 2020) GeneXpert Bladder specimens embedded in paraffin (-) |
| Strain drug sensitivity | Sensitive to SM, INH, RMP, EMB, PZA | Sensitive to SM, INH, RMP, EMB, PZA |
| Strains genotyping Spoligotyping MIRU-VNTR |
■■■■■■■■■■■■■■■■■■■■□□□□■■■■■■■■□□□□■■■■■■■ LAM9 42 233464236654438 |
■■■■■■■■■■■■■■■■■■■■■■■■■■■■■■■■□□□□■■■■■■■ T1 51 324443322564234 |
| TB treatment | INH+RMP+PZA+EMB | No data |
| COVID-19 | ||
| Diagnostic tests | Throat and nasal swab | Throat and nasal swab |
| Genetic assay | Vitassay qPCR SARS-CoV-2 (+) (27 May 2020) |
Vitassay qPCR SARS-CoV-2 (+) (27 May 2020) |
| Clinical symptoms | Cough, fever of 39.6 °C, shortness of breath, and a sore throat | No symptoms |
| Radiological observations | Chest X-ray: bilateral areas of fusing parenchymal-atelectatic densities in the lungs, predominant in the upper and middle fields CT scans: Extensive lesions parenchymal-atelectatic; thick-walled cavities filled with masses of tissue decay in the upper lobes płuc; areas of tree-in-bud-appearance in segment 3 of the left lung and in the apex of segment 6 of the right and left lung; fluid in the pleural cavity; tree-in-bud-appearance in the apex of segment 6 of the right lung and in segments 6–9 of the left lung |
No data |
| Other diagnostic tests | - | Histopathological examination of bladder specimens revealed granular lesions with purulent inflammation and necrotizing purulent masses of tissue |
| OUTCOME | Unsuccessful treatment, death (31 May 2020) | Successful treatment, outpatient care |