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Treatment algorithm for neutropenic LGLL patients. *MTX to be preferred in STAT3 Y640F patients; ANC: absolute neutrophil count; CR: complete response; CyA: Cyclosporine A; CTX: cyclophosphamide; G-CSF: granulocyte-colony stimulating factor; MTX: methotrexate; PD: progressive disease; PR: partial response; R/R: relapsed/refractory; SD: stable disease.
