Table 1.
PD-L1 expression and cell content in paired histological and cytological non-small cell lung cancer specimens.
| Characteristics | All Cases | PD-L1 Positive Tumour Cells |
Cell Content Number of Tumour Cells |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| <1% | 1–4% | 5–9% | 10–49% | ≥50% | 100–300 | >300–500 | >500–1000 | >1000 | ||
| Histological subtype, n (%) | ||||||||||
| Adenocarcinoma | 66/100 | |||||||||
| Cytological samples | 25/66 (38) |
7/66 (11) |
5/66 (8) |
8/66 (12) |
21/66 (32) |
34/66 (52) |
12/66 (18) |
5/66 (8) |
15/66 (23) |
|
| Biopsy samples | 26/66 (39) |
8/66 (12) |
5/66 (8) |
7/66 (11) |
20/66 (30) |
34/66 (52) |
11/66 (17) |
16/66 (24) |
5/66 (8) |
|
| Squamous cell carcinoma | 34/100 | |||||||||
| Cytological samples | 22/34 (65) |
1/34 (3) |
2/34 (6) |
3/34 (9) |
6/34 (18) |
13/34 (38) |
11/34 (32) |
4/34 (12) |
6/34 (18) |
|
| Biopsy samples | 18/34 (53) |
4/34 (12) |
0/34 (0) |
7/34 (21) |
5/34 (15) |
10/34 (29) |
7/34 (21) |
7/34 (21) |
10/34 (29) |
|
| Type of cytological specimen, n (%) | ||||||||||
| Pleural fluid | 19/100 | 9/19 (47) |
3/19 (16) |
2/19 (11) |
1/19 (5) |
4/19 (21) |
3/19 (16) |
5/19 (26) |
2/19 (11) |
9/19 (47) |
| Bronchial brush | 17/100 | 11/17 (65) |
0/17 (0) |
1/17 (6) |
1/17 (6) |
4/17 (24) |
8/17 (47) |
2/17 (12) |
5/17 (29) |
2/17 (12) |
| Bronchoalveolar lavages | 64/100 | 27/64 (42) |
5/64 (8) |
4/64 (6) |
9/64 (14) |
19/64 (30) |
36/64 (56) |
16/64 (25) |
2/64 (3) |
10/64 (16) |
| Type of biopsy, n (%) | ||||||||||
| Bronchial biopsy | 80/100 | 36/80 (45) |
10/80 (13) |
4/80 (5) |
9/80 (11) |
21/80 (26) |
37/80 (46) |
15/80 (19) |
18/80 (23) |
10/80 (13) |
| Transthoracic core biopsy | 20/100 | 8/20 (40) |
2/20 (10) |
1/20 (5) |
5/20 (25) |
4/20 (20) |
7/20 (35) |
3/20 (15) |
5/20 (25) |
5/20 (25) |