Figure 3.
Deletion of PaCrd1 dramatically affects PL metabolism and lifespan. (A): PL composition of isolated mitochondria of 7-day-old wild-type (WT) and ΔPaCrd1 strains grown under glycolytic conditions. Data represent relative proportion of total lipids. Significantly (p < 0.05) increased or reduced PLs are marked with green and red boxes, respectively. Exact values can be found in supplementary material (Table S1). For abbreviations, see caption of Figure 1. (B): PE/PC ratio of wild type and ΔPaCrd1. Data represent mean ± SD (n = 5). *** p < 0.001. (C): Lifespan analysis of wild type (n = 43) and ΔPaCrd1 (n = 16) grown on M2 medium at 27 °C.