Table 4.

Comparison of histopathological features between the groups, depending on a 50% deterioration of eGFR. The statistically significant parameters are bolded in the table.

MEST-C	eGFR Reduction >50%		p-Value
	No (N = 73)	Yes (N = 7)
M1	59 (80%)	7 (100%)	0.24
E1	19 (26%)	5 (71%)	0.03
S1	38 (52%)	2 (29%)	0.39
T2	1 (1.4%)	0 (0%)	0.1
C1-2	7 (9.6%)	1 (14%)	0.7
Interstitial inflammation—1–2	39 (53%)	6 (86%)	0.21
Interstitial fibrosis (%)	6.6 ± 2.2	11.1 ± 3.2	0.02