Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 30;11(10):1808. doi: 10.3390/diagnostics11101808

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Specific recognition of the S1 domain, the nucleocapsid, and the receptor-binding domain by serum samples from patients with confirmed COVID-2019. (A) Expi293 cells were transfected with constructs pcDNA3.1/S1 and pcDNA3.1/N, and 24 h post-transfection, the expression of culture samples was evaluated by an immunofluorescence assay after treatment with human serum samples from patients with COVID-19, and those from pre-pandemic serum samples were evaluated as well. (B) The three recombinant proteins were also assessed using Western blotting. Culture samples were harvested at 24 h post-transfection and then analyzed with human serum samples from patients with confirmed COVID-19, as well as those from pre-pandemic serum. Lane 1, molecular weight marker; lane 2, eluted proteins.