Table 2.
Descriptive statistics of cholesterol, HDL-C, LDL-C, and triglycerides at the different time points. Means and interquartile ranges are shown, and p-values indicate if the lipid values differ at the four time points. Post-hoc comparisons of pairwise differences in lipid levels are illustrated with Cliff’s delta (d) as effect size.
| Time Point | Cholesterol (mmol/L) |
HDL-C (mmol/L) |
LDL-C (mmol/L) | Triglycerides (mmol/L) |
|---|---|---|---|---|
| Baseline | 4.1 (3.5–5.1) | 1.2 (1.01.6) | 2.2 (1.7–2.9) | 1.3 (1.0–2.0) |
| Pre-operative | 4.3 (3.7–5.0) | 1.1 (0.9–1.4) | 2.7 (2.1–3.4) | 1.3 (1.0–1.9) |
| Intra-operative | 2.8 (2.33.4) | 0.7 (0.6–0.9) | 1.7 (1.3–2.2) | 0.5 (0.4–0.7) |
| Post-operative | 2.6 (2.2–3.3) | 0.9 (0.8–1.1) | 1.5 (1.1–2.0) | 1.0 (0.7–1.3) |
| P ‡ | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
| Post-hoc comparisons (d *) | ||||
| Baseline vs. Pre-operative |
−0.08 (−0.20, 0.03) † |
0.24 (0.12, 0.35) † |
−0.33 (−0.44, −0.22) † |
0.01 (−0.10, 0.13) † |
| Baseline vs. Intra-operative |
0.73 (0.65, 0.79) † |
0.82 (0.75, 0.87) † |
0.33 (0.22, 0.44) † |
0.86 (0.80, 0.90) |
| Baseline vs. Post-operative |
0.74 (0.66, 0.80) † |
0.63 (0.53, 0.70) † |
0.45 (0.35, 0.55) † |
0.41 (0.30, 0.50) † |
| Intra-operative vs. Post-operative | 0.08 (−0.04, 0.19) |
−0.39 (−0.49, −0.28) † |
0.17 (0.05, 0.28) † |
−0.66 (−0.74, −0.58) † |
| Pre-operative vs. Intra-operative | 0.75 (0.68, 0.82) † |
0.72 (0.64, 0.79) † |
0.66 (0.57, 0.73) † |
0.86 (0.81, 0.90) † |
| Pre-operative vs. Post-operative | 0.77 (0.69, 0.82) † |
0.46 (0.36, 0.55) † |
0.73 (0.65, 0.79) † |
0.40 (0.29, 0.50) † |
‡ Friedman Test; * Mean and 95% confidence intervals are shown (note that d is positive when the lipid levels of the first time point of the comparison are greater than the levels of the second time point and vice versa; † Statistically significant (all p < 0.0001) after Wilcoxon signed-rank test with a Bonferroni adjustment for multiple comparisons.