Table 1.
Advantages and disadvantages of selected vaccine platforms.
| Design | Upscaling | Re-Using Established GMP Conditions | Theoretical Safety Concerns | |
|---|---|---|---|---|
| Recombinant viral vector (adenovirus) | Not easy | To be optimized | Not guaranteed | Recombination/persistence/integration |
| ivt mRNA | Easy | Easy | Guaranteed | None |
| Proteins/ sugars |
Not easy | To be optimized | Not guaranteed | None |
| Inactivated viruses | Easy | To be optimized | Not guaranteed | None |