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. 2021 Sep 30;11(10):1812. doi: 10.3390/diagnostics11101812

Table 6.

Deep learning clinical outcome prediction results.

Ventilation Requirement Mortality
Unadjusted Histogram Matching Unadjusted Histogram Matching
Sensitivity CXR 0.55 ± 0.09 0.64 ± 0.09 0.56 ± 0.15 0.59 ± 0.13
CLC 0.63 ± 0.08 0.61 ± 0.01 0.58 ± 0.17 0.67 ± 0.09
REM 0.54 ± 0.08 0.68 ± 0.05 0.66 ± 0.07 0.64 ± 0.07
REM CLC 0.58 ± 0.09 0.62 ± 0.08 0.61 ± 0.14 0.77 ± 0.07
RAD 0.63 ± 0.06 0.66 ± 0.04 0.58 ± 0.12 0.59 ± 0.12
RAD CLC 0.62 ± 0.07 0.67 ± 0.07 0.59 ± 0.07 0.69 ± 0.08
Specificity CXR 0.72 ± 0.08 0.73 ± 0.07 0.72 ± 0.07 0.74 ± 0.04
CLC 0.66 ± 0.08 0.76 ± 0.05 0.65 ± 0.06 0.71 ± 0.09
REM 0.59 ± 0.05 0.63 ± 0.02 0.58 ± 0.08 0.73 ± 0.07
REM CLC 0.65 ± 0.07 0.68 ± 0.06 0.63 ± 0.08 0.60 ± 0.09
RAD 0.69 ± 0.06 0.75 ± 0.06 0.67 ± 0.03 0.76 ± 0.03
RAD CLC 0.69 ± 0.06 0.78 ± 0.05 0.71 ± 0.02 0.67 ± 0.03
AUC CXR 0.70 ± 0.07 0.75 ± 0.02 0.72 ± 0.07 0.75 ± 0.04
CLC 0.69 ± 0.03 0.77 ± 0.02 0.70 ± 0.07 0.74 ± 0.04
REM 0.61 ± 0.03 0.71 ± 0.02 0.67 ± 0.04 0.76 ± 0.04
REM CLC 0.64 ± 0.02 0.72 ± 0.02 0.68 ± 0.02 0.77 ± 0.01
RAD 0.70 ± 0.03 0.77 ± 0.03 0.69 ± 0.07 0.74 ± 0.06
RAD CLC 0.72 ± 0.02 0.78 ± 0.02 0.71 ± 0.04 0.75 ± 0.07

All columns used preprocessed patient CXRs as inputs to DL networks in addition to: CLC―clinical features including patient age and sex; REM―radiomic-embedded feature maps; RAD―concatenation of radiomic features to DL feature outputs. Bold text indicates highest metrics obtained.