Table 2. Laboratory parameters on admission to the ICU according to hospital outcome.
| Survivors | Non-survivors | p-value | |
|---|---|---|---|
| N | 269 | 75 | |
| Inflammatory parameters | |||
| White blood cell count, x109/L | 7.6 (5.7–4.5) | 8.8 (6.5–13.7) | 0.011 |
| C-reactive protein, mg/L | 123 (57–176) | 155 (93–243) | 0.003 |
| Procalcitonin, ng/ml | 0.21 (0.12–0.55) | 0.56 (0.28–2.5) | <0.001 |
| Lactate dehydrogenase, IU/L | 410 (315–508) | 493 (397–633) | <0.001 |
| Ferritin, ng/mL | 926 (565–1645) | 1127 (710–2745) | 0.005 |
| D-dimer, mg/L | 0.9 (0.5–1.6) | 1.7 (0.8–3.3) | <0.001 |
| Organ function parameters | |||
| Bilirubin, total, μmol/L | 9 (6.6–12.3) | 9.7 (6.4–13.4) | 0.338 |
| Bilirubin, direct, μmol/L | 4.4 (3.2–6.4) | 5.6 (3.6–9.8) | 0.001 |
| Creatinine, μmol/L | 79 (67–94) | 99 (72–229) | <0.001 |
| Urea, mmol/L | 5 (3.6–6.7) | 7.5 (4.6–15.3) | <0.001 |
| Serum albumin, g/L | 29 (26–33) | 26 (22–29) | <0.001 |
| Alkaline phosphatase, IU/L | 72 (57–95) | 92 (63–126) | 0.001 |
| ALT, IU/L | 34 (24–55) | 28 (20–50) | 0.236 |
| AST, IU/L | 41 (30–62) | 45 (32–63) | 0.588 |
| Blood picture | |||
| Red blood cell count, x1012/L | 4.6 (4.1–5.1) | 4.3 (3.8–4.9) | 0.046 |
| Platelet count, x109/L | 213 (171–287) | 207 (152–242) | 0.035 |
| Hemoglobin level g/l | 130 (116–141) | 120 (104–136) | 0.012 |
| Hematocrit, % | 38 (35–42) | 36 (31–40) | 0.015 |
| Lymphocyte count, x109/L | 1 (0.8–1.3) | 0.8 (0.5–1.1) | 0.001 |
| Neutrophil count, x109/L | 5.9 (4.2–8.8) | 7.3 (4.9–12.6) | 0.002 |
| Neutrophil:lymphocyte ratio | 6.0 (4.1–9.4) | 11.9 (5.4–17.4) | <0.001 |
Data presented as median (interquartile range).
ALT: alanine aminotransferase, AST: aspartate transaminase, IU: international unit.
Missing values (survivors/non-survivors): white blood cell count:7/1, procalcitonin:0/1, LDH:2/1, ferritin:0/1, D-dimer:1/4, bilirubin-direct:7/0, bilirubin-total:4/0, creatinine:0/1, urea:0/1, serum albumin:3/1, alkaline phosphatase: 6/0, ALT:4/0, AST:5/0, red cell count: 7/1, platelet count: 8/2, hemoglobin: 2/0, lymphocyte count: 7/1, neutrophil count: 7/1.