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. 2021 Sep 28;12(10):1525. doi: 10.3390/genes12101525

Table 1.

Follicular development process and related genes.

Morphogenesis Process Genes
From ovarian stem cell to ovigerous cords Wnt4, Rspo1, Bmp2, Bmp4, Bmp8a, Smads, KltL, Oct4, Nanos1, Nanos3, Kit, Dazl, Bcl-x, Pin1, Pog, Gja1, Bax
Follicular assembly Msx1, Msx2, Dicer, Notch, Follistain, Stra8, Stag3, Syce1, Sycp2l, Spo11, Msh4, Msh5, Dmc1, Rec8, Atm, Lsh, Cdk2, Cbep, Hsf1, Fanc-a, Fanc-c, Fanc-g, Bcl2, Brca1, Mcl1, Gdf9, Bmp15
Primordial follicles formation and growth Foxl2, Ccn2, Cyp19a1, KitL, p27kip1, Figla, Pdk1, Mcm8, Foxo3, Pten, Sohlh1, Sohlh2, Lhx8, Nobox8, Ybx2, Tsc1/2, Diaph2/3, Ngf, Nt3, Nt4, Bdnf, Ntrk1, Ntrk2, Ntrk3, Birc1, Becn1, Atg7
Secondary follicle formation Gdf9, Bmp15, Zp1, Zp2, Zp3, Cx43, Rspo2, Inha, Taf4b
Advance to latter stages Esr1, Fshr, Nppc, Nprb, Kras, Erk1/2, Egfr, Bax, Ahr, Clast4, Polg