From ovarian stem cell to ovigerous cords |
Wnt4, Rspo1, Bmp2, Bmp4, Bmp8a, Smads, KltL, Oct4, Nanos1, Nanos3, Kit, Dazl, Bcl-x, Pin1, Pog, Gja1, Bax
|
Follicular assembly |
Msx1, Msx2, Dicer, Notch, Follistain, Stra8, Stag3, Syce1, Sycp2l, Spo11, Msh4, Msh5, Dmc1, Rec8, Atm, Lsh, Cdk2, Cbep, Hsf1, Fanc-a, Fanc-c, Fanc-g, Bcl2, Brca1, Mcl1, Gdf9, Bmp15
|
Primordial follicles formation and growth |
Foxl2, Ccn2, Cyp19a1, KitL, p27kip1, Figla, Pdk1, Mcm8, Foxo3, Pten, Sohlh1, Sohlh2, Lhx8, Nobox8, Ybx2, Tsc1/2, Diaph2/3, Ngf, Nt3, Nt4, Bdnf, Ntrk1, Ntrk2, Ntrk3, Birc1, Becn1, Atg7
|
Secondary follicle formation |
Gdf9, Bmp15, Zp1, Zp2, Zp3, Cx43, Rspo2, Inha, Taf4b
|
Advance to latter stages |
Esr1, Fshr, Nppc, Nprb, Kras, Erk1/2, Egfr, Bax, Ahr, Clast4, Polg
|