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. 2021 Sep 30;12(10):1559. doi: 10.3390/genes12101559

Table 1.

Publications of conceptual components of STRmix™ modelling.

Algorithms, Scientific Principles and Methods Version Introduced Reference
Allele and stutter peak height variability as separate constants within the MCMC V2.0 [15]
Peak height variability as random variables within the MCMC V2.3 [196]
Model for calibrating laboratory peak height variability V2.0 [196]
Application of a Gaussian random walk to the MCMC process V2.3 [205]
Modelling of back stutter by regressing stutter ratio against allelic designation V2.0 [156,197,206,207]
Modelling of back stutter by regressing stutter ratio against LUS V2.3 [156,162,206,207]
Modelling of forward stutter V2.4 [157]
Modelling of allelic drop-in using a simple exponential or uniform distribution V2.0 [15]
Modelling of allelic drop-in using a γ distribution V2.3 [13]
Modelling of degradation and dropout V2.0 [154]
Modelling of the uncertainties in the allele frequencies using the HPD V2.0 [208]
Modelling of the uncertainties in the MCMC V2.3 [171,208,209]
Database searching of mixed DNA profiles V2.0 [190]
Familial searching of mixed DNA profiles V2.3 [168]
Relatives as alternate contributors under the defence proposition V2.3 [168]
Modelling expected stutter peak heights in saturated data V2.3 [157]
Taking into account the ‘factor of two’ in LR calculations V2.3 [104]
Model for incorporating prior beliefs in mixture proportions V2.3 [210]
Combining DNA profiles produced under different conditions into a single analysis V2.5 [155]
Assigning a range for the number of contributors to a DNA profile V2.6 [164]
Mixture-to-mixture comparison to identify common DNA donors V2.7 [20]
A top-down DNA search approach V2.8 [74]
The diagnostic outputs of STRmix™ V2.3 [211]