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. 2021 Oct 17;18(20):10892. doi: 10.3390/ijerph182010892

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Markers of oxidative stress in myocardium. (A) Marginal higher concentration of mitochondrial superoxide formation (DHE HPLC) in the diabetic (IDDM/NIDDM) group versus control (CTR). (B) No difference in ALDH-2 activity after oxidative inactivation in the IDDM/NIDDM versus CTR group. 2-HE, 2-hydroxyethidium; ALDH-2, mitochondrial aldehyde dehydrogenase. Data are the mean ± SD of n = 38 (CTR) and 20 (IDDM/NIDDM) (A) and n = 16 (CTR) and 11 (IDDM/NIDDM) (B) patients. Mann–Whitney test in (A) and unpaired t-test in (B). CTR, control; IDDM, insulin-dependent diabetes mellitus type 2; NIDDM, non-insulin dependent diabetes mellitus type 2.